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SCORE
Lumbrokinase
Fibrinolysis · Circulation · Cardiovascular
Tier 3 — Trending
What it is
A fibrinolytic enzyme extracted from earthworms that dissolves fibrin, a protein involved in blood clotting. Similar mechanism to nattokinase but potentially more potent. Small clinical trials show it reduces fibrinogen levels and improves blood viscosity. Used extensively in Traditional Chinese Medicine. Do not combine with blood thinners as it significantly increases bleeding risk.
Efficacy
3/5
Safety
3/5
Research
2/5
Onset
3/5
Cost
2/5
Drug-int.
2/5
Dose
40–80 mg/day (600,000–1,200,000 IU); AVOID with anticoagulants — additive bleeding risk
Time of day & tips
Take on an empty stomach, at least 30 min before meals. Never combine with warfarin, aspirin, or blood thinners. Stop 1–2 weeks before surgery.
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