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SCORE
Lactobacillus plantarum 299v
Probiotic strain · IBS · Iron absorption
Tier 2 — Promising
What it is
One of the most-studied L. plantarum strains. Bork-Jensen RCTs show IBS symptom improvement; Hoppe trials show enhanced non-heme iron absorption when co-dosed with iron + vitamin C. Safe in immunocompetent adults; standard probiotic cautions apply in deeply immunosuppressed patients (TNF inhibitors, post-transplant).
Efficacy
4/5
Safety
4/5
Research
4/5
Onset
3/5
Cost
3/5
Drug-int.
4/5
Dose
10 billion CFU/day
Time of day & tips
Take with iron + vitamin C if treating iron deficiency; refrigerate where required; expect 4-8 weeks for IBS effect.
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