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Lactobacillus acidophilus

Gut · Vaginal health · Cholesterol
Tier 2 — Promising

What it is

One of the most widely consumed probiotic strains worldwide with over 50 years of clinical research. A 2024 review found the NCFM strain significantly reduces lactose intolerance symptoms and improves vaginal flora in women prone to yeast infections. Also modestly lowers LDL cholesterol. Found naturally in yoghurt and fermented foods. Very safe with no serious side effects reported even in immunocompromised patients in most studies.

Efficacy
3/5
Safety
5/5
Research
4/5
Onset
3/5
Cost
3/5
Drug-int.
5/5

Dose

1–10 billion CFU/day; NCFM and La-5 strains have strongest clinical evidence

Time of day & tips

Take in the morning with or just after a meal — food buffers stomach acid and improves probiotic survival. Refrigerate if required. Separate from antibiotics by at least 2 hours.

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