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79
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Inositol (high-dose, psychiatric)

OCD · Panic disorder · Mood
Tier 2 — Promising

What it is

At doses of 12 to 18 g per day, inositol has strong evidence as an add-on treatment for obsessive-compulsive disorder and panic disorder — comparable to SSRI effects in direct head-to-head trials. The brain uses inositol as a second messenger in serotonin signaling pathways, explaining its mood effects. Very safe with no toxicity even at high doses. Distinct from the lower-dose PCOS use.

Efficacy
4/5
Safety
5/5
Research
3/5
Onset
2/5
Cost
4/5
Drug-int.
5/5

Dose

12–18 g/day in 3 divided doses for OCD or panic disorder; 2–4 g/day for PCOS; extremely safe

Time of day & tips

Powder form dissolves easily in water. Split into 3 daily doses for psychiatric use. No significant drug or food interactions. Can be combined with NAC. Allow 4–6 weeks.

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