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Inositol myo-form (PCOS/metabolic)

PCOS · Insulin sensitivity · Ovulation

Tier 2 — Promising

What it is

One of the best-supported supplements for women with PCOS. At 2 to 4 g per day, multiple trials confirm it improves insulin sensitivity, helps restore regular ovulation, and lowers elevated androgens. The 40:1 ratio of myo to D-chiro-inositol mirrors what the body naturally produces. Also shows promise for mood and anxiety at higher doses. Very safe with minimal side effects even at 18 g daily.

Efficacy

4/5

Safety

5/5

Research

3/5

Onset

2/5

Cost

4/5

Drug-int.

5/5

Dose

2,000–4,000 mg/day myo-inositol; 40:1 myo:D-chiro combination preferred for PCOS

Time of day & tips

Can be taken with or without food. Split into 2 doses (morning and evening) for steady levels. Mild GI discomfort possible at higher doses — start low and increase gradually.

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