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Iberogast (STW 5)

Functional dyspepsia · Multi-herb · German RCT

Tier 2 — Promising

What it is

Standardised liquid extract of nine herbs (bitter candytuft, angelica, chamomile, caraway, milk thistle, lemon balm, peppermint, celandine, liquorice). Multiple RCTs in functional dyspepsia and IBS show effect comparable to over-the-counter prokinetics. The original STW 5 formula was reformulated in 2020 (STW 5-II) to remove celandine and liquorice after rare hepatotoxicity case reports — choose products containing the new formulation if available. Avoid in cholestatic liver disease.

Efficacy

4/5

Safety

3/5

Research

4/5

Onset

2/5

Cost

3/5

Drug-int.

3/5

Dose

20 drops TID before meals (8 weeks)

Time of day & tips

STW 5-II formulation is preferred; avoid in cholestatic liver disease or pregnancy; report any abdominal pain promptly.

Sensitive populations: This supplement's evidence base touches pregnancy, pediatric, or other sensitive populations. Confirm any change with your healthcare provider before use.

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