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Hydroxytyrosol (olive extract)

Cardiovascular · Antioxidant · EFSA approved
Tier 2 — Promising

What it is

The primary polyphenol in extra virgin olive oil, responsible for most of its cardiovascular benefits. EFSA approved a health claim: 5 mg per day protects blood lipids from oxidative damage. A 2024 review found it significantly lowers LDL oxidation and cardiovascular inflammation markers. More potent as an antioxidant than resveratrol and vitamin E. Very safe with no known drug interactions.

Efficacy
3/5
Safety
5/5
Research
3/5
Onset
2/5
Cost
3/5
Drug-int.
5/5

Dose

5–20 mg/day hydroxytyrosol from olive extract (EFSA-approved health claim at 5 mg/day minimum)

Time of day & tips

Take with a meal containing fat for best absorption. Morning with breakfast is convenient. No drug interactions. A diet rich in extra virgin olive oil also provides this compound daily.

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