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Horse chestnut (Aesculus)
Venous insufficiency · Leg swelling
Tier 3 — Trending
What it is
One of the best-studied herbal treatments for chronic venous insufficiency. A Cochrane review confirmed aescin-standardised extract reduces leg swelling and pain vs placebo. Works by reducing capillary permeability and improving venous tone. Raw horse chestnuts are toxic — only standardised extracts should be used. Avoid with blood thinners.
Efficacy
3/5
Safety
3/5
Research
3/5
Onset
2/5
Cost
3/5
Drug-int.
3/5
Dose
300 mg twice daily standardised to 50 mg aescin; raw seeds are toxic and must never be eaten
Time of day & tips
Take with food. Only use standardised extracts — never eat raw horse chestnuts. Avoid with blood thinners. Elevate legs and stay hydrated alongside supplementation.
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