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Hops (Humulus lupulus)

Sleep · Phytoestrogen · GABAergic
Tier 3 — Trending

What it is

Hops cones contain 8-prenylnaringenin and methylbutenol — mildly sedating and weakly oestrogenic. Most clinical evidence is for hops + valerian combinations (e.g., Ze 91019) for sleep onset. Standalone evidence is thinner. Avoid in oestrogen-sensitive cancers, hormonal contraceptives, and HRT (additive).

Efficacy
2/5
Safety
3/5
Research
2/5
Onset
3/5
Cost
4/5
Drug-int.
3/5

Dose

100-300 mg dried-extract pre-bed; or 0.5 g cone in tea

Time of day & tips

Combine with valerian or lemon balm; avoid with SSRIs/benzo-class sedatives (additive sedation).

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