67
SCORE
Hesperidin
Circulation · Venous insufficiency
Tier 2 — Promising
What it is
A citrus flavonoid found naturally in oranges and lemons that supports healthy blood vessel function. Multiple European trials show it significantly improves symptoms of chronic venous insufficiency including leg heaviness, swelling, and cramps. Commonly combined with diosmin in products sold throughout Europe for vein health. Very safe with no serious side effects.
Efficacy
3/5
Safety
5/5
Research
2/5
Onset
2/5
Cost
3/5
Drug-int.
5/5
Dose
500 mg/day hesperidin or 900 mg/day diosmin-hesperidin complex
Time of day & tips
Take with food. Timing is flexible. Safe to combine with other vein-support supplements like rutin or vitamin C.
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