Hericium erinaceus mycelium (Amyloban 3399)
What it is
Unlike fruiting body extracts, the mycelium-derived product Amyloban 3399 standardises amycenone, a unique compound found only in the mycelial stage. Small Japanese trials found it improved cognitive function and reduced depression in patients with mild cognitive impairment. Different active compounds from fruiting body products. Limited evidence but a distinct product from standard lion's mane supplements.
Dose
500–1,500 mg/day Amyloban 3399 standardised to amycenone; different active profile from fruiting body extracts
Time of day & tips
This is a different product from fruiting body lion's mane — active compounds differ. Japanese studies used specific Amyloban 3399 preparation. Allow 8–12 weeks. Most generic mycelium-on-grain products lack meaningful amycenone.
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