60
SCORE
Glucosamine / Chondroitin
Joint pain
Tier 2 — Promising
What it is
The major GAIT trial (1,583 people) found glucosamine was no better than placebo for joint pain. Chondroitin shows modest arthritis benefits in some people, but evidence is mixed overall. Despite being the most popular joint supplement, newer options like Boswellia and collagen type II have stronger evidence. Very safe if you choose to try it.
Efficacy
2/5
Safety
4/5
Research
4/5
Onset
1/5
Cost
3/5
Drug-int.
5/5
Dose
Glucosamine sulfate 1,500 mg/day + Chondroitin sulfate 1,200 mg/day; trial 3 months
Time of day & tips
Take with food to minimise stomach upset. Can be taken with or without a full meal. No major drug interactions, but glucosamine may mildly raise blood sugar in diabetics.
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