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Eggshell membrane (NEM)

Joint · Connective tissue · Collagen

Tier 2 — Promising

What it is

The translucent membrane lining the inside of chicken eggshells, supplied as a partially hydrolysed powder (Natural Eggshell Membrane, NEM). It supplies type I, V, and X collagen, glycosaminoglycans (hyaluronic acid, chondroitin), and elastin — a composition matching joint and connective-tissue ECM. Multiple RCTs show improvements in joint pain, stiffness, and flexibility within 7-10 days at 500 mg/day — faster than glucosamine/chondroitin. Shellfish-free alternative to marine-sourced joint supplements. Avoid with egg allergy.

Efficacy

3/5

Safety

5/5

Research

3/5

Onset

3/5

Cost

3/5

Drug-int.

4/5

Dose

500 mg NEM daily (standardised Natural Eggshell Membrane)

Time of day & tips

Take with or without food; much faster onset than glucosamine/chondroitin; single-dose convenience; contraindicated in egg allergy; effects typically apparent within 2 weeks

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