73
SCORE
Diosmin
Varicose veins · Hemorrhoids · Venous insufficiency
Tier 2 — Promising
What it is
A flavonoid prescribed across Europe for chronic venous insufficiency and hemorrhoids. Multiple large trials show it significantly reduces leg heaviness, swelling, and pain from varicose veins. The micronized form (MPFF, as in Daflon) has the strongest evidence. Also effective for acute hemorrhoid flares at higher doses. Very well tolerated with minimal side effects in clinical use.
Efficacy
4/5
Safety
4/5
Research
3/5
Onset
2/5
Cost
3/5
Drug-int.
5/5
Dose
500 mg × 2 daily (micronized); 1,000 mg × 3 daily for 4 days then 1,000 mg × 2 for acute hemorrhoids
Time of day & tips
Take with meals. For chronic venous issues take consistently over months. The micronized form (Daflon) works best. Drink plenty of water and stay active.
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