Dihydromyricetin (DHM)
What it is
A flavonoid from the Japanese raisin tree that has been proposed to accelerate alcohol metabolism. Small human trials (e.g. Chen 2020 at 300 mg) have been mostly negative or inconsistent for hangover severity, while animal and mechanistic work suggest upregulation of liver ADH and ALDH enzymes and possible liver-protective effects. Generally well tolerated short-term. Does not reduce acute impairment. Human evidence for hangover prevention remains weak.
Dose
300–600 mg before or during alcohol consumption; 600 mg studied in clinical trials
Time of day & tips
Take with water 30–60 min before drinking, and a second dose just before bed if you continue drinking. Most effective when taken before the first drink. Do not use as a reason to drink more — DHM reduces acetaldehyde but not BAC or impairment.
Compare or learn more
Compare with another supplement →
Browse by symptom →
Open the full interactive view →