Coriolus versicolor PSP/PSK (turkey tail polysaccharide)
What it is
PSK (Krestin) is an approved adjunctive cancer treatment in Japan with over 30 years of clinical use. PSP is a related polysaccharide from the same mushroom. Multiple trials show improved 5-year survival rates in gastric and colorectal cancer when used alongside conventional treatment. A 2024 trial also found PSP significantly improved gut microbiome diversity. Not a standalone cancer treatment.
Dose
1,000–3,000 mg/day PSK or PSP standardised extract; studied as adjunct to conventional cancer treatment, not standalone
Time of day & tips
Must be used alongside conventional cancer treatment — never as a replacement. Discuss with your oncologist. Choose products standardised to polysaccharide-K or polysaccharopeptide content. Generally well tolerated.
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