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SCORE
Cissus quadrangularis
Bone healing · Joint · Weight
Tier 3 — Trending
What it is
Helps speed up bone fracture healing and reduces arthritis joint pain. A 2024 review of 9 trials confirmed these benefits with clinical significance. A traditional Ayurvedic plant now backed by modern clinical evidence. The standardized extract form (3% ketosterones) has the most research. Generally well tolerated with a good safety profile.
Efficacy
3/5
Safety
4/5
Research
2/5
Onset
2/5
Cost
2/5
Drug-int.
4/5
Dose
500–1,000 mg/day standardised extract (3% ketosterones)
Time of day & tips
Take with water and food to reduce stomach upset. Can be taken any time of day. Consistent daily use over several weeks is needed for bone and joint benefits.
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