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SCORE

Chamomile extract (Matricaria chamomilla)

Anxiety · Sleep · Digestive
Tier 1 — Strong Evidence

What it is

One of the most consumed herbal teas worldwide with evidence for anxiety and sleep. The Mao et al. 2016 Phytomedicine trial (3-arm RCT, long-term GAD) found chamomile significantly reduces anxiety scores with tolerability comparable to low-dose benzodiazepines in one head-to-head comparison. Contains apigenin, which binds GABA receptors. The extract form provides more consistent dosing than tea. Very safe with an excellent long-term safety record and no dependency.

Efficacy
3/5
Safety
5/5
Research
3/5
Onset
3/5
Cost
4/5
Drug-int.
5/5

Dose

220–1,100 mg/day standardised extract or 3–4 cups chamomile tea; safe long-term

Time of day & tips

Drink as tea or take capsule 30–60 min before bed. Avoid if allergic to ragweed or daisies. Very safe for long-term nightly use.

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