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Centella asiatica (Gotu kola, standardised TTFCA)

Venous insufficiency · Wound healing · Cognition

Tier 2 — Promising

What it is

Standardised to triterpene fraction (TTFCA) containing asiaticoside and madecassoside. Cochrane reviews confirm it improves symptoms of chronic venous insufficiency including leg heaviness and swelling. Also promotes wound healing by stimulating collagen synthesis. Traditional Ayurvedic use for cognition is supported by small trials showing improved working memory. Not to be confused with kola nut.

Efficacy

3/5

Safety

4/5

Research

2/5

Onset

2/5

Cost

3/5

Drug-int.

4/5

Dose

60–120 mg/day TTFCA (total triterpenic fraction of Centella asiatica); take in divided doses

Time of day & tips

Take with meals in divided doses. Allow 4–8 weeks for venous insufficiency benefits. Rare cases of contact dermatitis reported. Not the same as kola nut — contains no caffeine.

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