69
SCORE
Capsinoids (CH-19 sweet pepper)
Weight management · Thermogenesis · Metabolic
Tier 2 — Promising
What it is
Non-pungent analogues of capsaicin found in CH-19 sweet pepper. Unlike capsaicin, capsinoids do not activate oral TRPV1 receptors (no burning sensation), but stimulate intestinal TRPV1, activating sympathetically-driven fat oxidation and thermogenesis. Meta-analyses show consistent energy expenditure increases of 50–100 kcal/day and enhanced fat oxidation, particularly from visceral fat. No cardiovascular stimulation or GI irritation. Currently the safest thermogenic supplement option available.
Efficacy
3/5
Safety
5/5
Research
2/5
Onset
4/5
Cost
3/5
Drug-int.
4/5
Dose
6–10 mg/day with meals
Time of day & tips
Most effective when caloric intake is controlled; combine with moderate aerobic exercise; no cycling required
Compare or learn more
Compare with another supplement →
Browse by symptom →
Open the full interactive view →