Calcium pantothenate (Vitamin B5)
What it is
The calcium salt of pantothenic acid, the stable and well-absorbed common supplemental form of vitamin B5. Essential for coenzyme A synthesis and acyl-carrier protein function — central to fatty acid metabolism, steroid hormone synthesis, and neurotransmitter production. High-dose pantothenic acid (2-10 g/day) has evidence for reducing acne vulgaris. Claims around 'adrenal support' in stress are mechanistically plausible but clinically unproven. Very safe even at high doses; diarrhoea is the main limit.
Dose
50–500 mg/day general use; up to 2–5 g/day split doses for acne
Time of day & tips
Very well tolerated; high doses cause loose stools so split across day; acne benefits take 4-8 weeks; often paired with L-carnitine or CoA for fatigue protocols
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