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SCORE
Calcium fructoborate
Bone · Joint · Testosterone
Tier 2 — Promising
What it is
A naturally occurring plant-sourced compound that delivers boron complexed with fructose. Multiple trials show it significantly reduces joint pain and inflammation markers in knee osteoarthritis. Also shown to modestly raise free testosterone and DHEA in men. Better absorbed and more bioavailable than inorganic boron forms. Delivers around 3 to 6 mg boron per studied dose.
Efficacy
3/5
Safety
4/5
Research
2/5
Onset
2/5
Cost
3/5
Drug-int.
4/5
Dose
110–220 mg/day calcium fructoborate (providing ~3–6 mg boron); better absorbed than boron glycinate
Time of day & tips
Take with food and water. Morning works well. Safe to use long-term at studied doses. Do not exceed 10 mg boron equivalent per day from all sources combined.
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