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72
SCORE

Cacao flavanols

Cardiovascular · Cognition · Blood pressure
Tier 2 — Promising

What it is

The COSMOS trial (21,442 adults) did not meet its primary composite cardiovascular endpoint, but the prespecified secondary analysis showed a 27% reduction in cardiovascular death with 500 mg/day cocoa flavanols vs placebo. EFSA upholds an approved health claim that 200 mg/day cocoa flavanols help maintain normal endothelial function. Also shows modest cognitive benefits in older adults (COSMOS-Mind sub-study). Regular chocolate contains very little flavanol due to Dutch-process alkalisation. Use a standardised cocoa flavanol supplement for reliable dosing.

Efficacy
3/5
Safety
5/5
Research
3/5
Onset
3/5
Cost
3/5
Drug-int.
5/5

Dose

200–500 mg/day cocoa flavanols (EFSA-approved); regular chocolate is NOT an equivalent source

Time of day & tips

Take with water or food. Morning works well. Avoid high-heat preparation — heat destroys flavanols. Regular chocolate is not an equivalent source.

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