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Biotin (low-dose, deficiency)

Hair · Nails · Metabolism
Tier 2 — Promising

What it is

At physiological doses (30–100 mcg), biotin corrects true deficiency symptoms like hair loss, brittle nails, and skin rash. Different from high-dose biotin (10,000+ mcg), which lacks evidence for hair growth in non-deficient people and can falsify lab tests.

Efficacy
3/5
Safety
5/5
Research
3/5
Onset
2/5
Cost
5/5
Drug-int.
5/5

Dose

30–100 mcg/day for deficiency; stop 48 hours before blood tests to avoid interference

Time of day & tips

Take with water, with or without food. Stop 48 hours before any blood test. Morning is a convenient time. No known food interactions at low doses.

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