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Beta-glucan (1,3/1,6)

Immunity · Cholesterol · Gut
Tier 2 — Promising

What it is

A natural fibre from oats, barley, and certain mushrooms that supports immune function and lowers cholesterol. EFSA approved a health claim for oat beta-glucan reducing LDL cholesterol at 3 g/day. The yeast-derived 1,3/1,6 form activates innate immune cells (macrophages, NK cells) most effectively. Very safe with no serious side effects.

Efficacy
3/5
Safety
5/5
Research
3/5
Onset
3/5
Cost
3/5
Drug-int.
5/5

Dose

250–500 mg/day yeast beta-glucan for immunity; 3 g/day oat beta-glucan for cholesterol

Time of day & tips

Take in the morning with water on an empty stomach (or with food if mild GI upset). Once daily is sufficient. No major food or supplement interactions at standard doses.

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