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SCORE
Avocado soybean unsaponifiables (ASU)
Joint · OA
Tier 3 — Trending
What it is
Extracted from avocado and soybean oils and studied for knee and hip OA. Several European RCTs found ASU reduced pain and improved function after 3–6 months. A large French trial showed reduced need for anti-inflammatory drugs. Effects are slow to appear (2–3 months). Widely prescribed in France but considered a supplement elsewhere.
Efficacy
2/5
Safety
4/5
Research
2/5
Onset
1/5
Cost
2/5
Drug-int.
5/5
Dose
300 mg/day ASU; effects take 2–3 months to appear; best studied for knee and hip OA
Time of day & tips
Take with a meal containing fat for best absorption. Once daily is fine. Allow 2–3 months before evaluating results.
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