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Apigenin

Sleep · Anxiety · Neuroprotection
Tier 3 — Trending

What it is

A compound found in chamomile that gently activates the brain's calming receptors. Provides mild anxiety relief without drowsiness or dependency. Also helps preserve NAD+, a molecule linked to aging. Human trial data is still limited, but the safety profile is excellent. Chamomile extract standardized for apigenin is the preferred form.

Efficacy
2/5
Safety
4/5
Research
2/5
Onset
4/5
Cost
3/5
Drug-int.
4/5

Dose

50–100 mg/day; chamomile extract standardised to apigenin preferred

Time of day & tips

Take 30–60 min before bed with water. Can be taken on an empty stomach. Avoid combining with alcohol or prescription sedatives.

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