Aniracetam
What it is
A fat-soluble racetam nootropic that modulates AMPA glutamate receptors and enhances cholinergic transmission. Approved as a prescription drug in some European countries for cognitive impairment. Small trials suggest anxiolytic effects mediated through dopamine and serotonin modulation. Not approved in the US. Short half-life of 1–2 hours requires multiple daily doses. Limited modern clinical data.
Dose
750–1,500 mg/day in 2–3 divided doses; take with fat for absorption; pair with a choline source
Time of day & tips
Must be taken with dietary fat — it is fat-soluble. Split into 2–3 daily doses due to short half-life. Pair with a choline source to avoid headaches. Not approved in the US — regulatory grey area.
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