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Andrographis paniculata

Immunity · Cold/Flu · Inflammation

Tier 2 — Promising

What it is

A systematic review by Hu and colleagues (2017) pooling 33 RCTs concluded andrographis appears to shorten the duration and severity of acute upper-respiratory infections when started early, though most trials were small and of low–moderate quality. Best evidence is for standardised extracts (≥30% andrographolides) taken within 36–48 hours of symptom onset. Well-tolerated short-term. Avoid in pregnancy — possible uterotonic effects. Not for daily prevention.

Efficacy

3/5

Safety

4/5

Research

3/5

Onset

4/5

Cost

3/5

Drug-int.

4/5

Dose

400 mg standardised extract (≥30% andrographolides) × 3 daily for 5 days at symptom onset

Time of day & tips

Take at the very first sign of symptoms — effectiveness drops sharply beyond 36 hours. Take with or after food to reduce bitter taste and stomach upset.

Sensitive populations: This supplement's evidence base touches pregnancy, pediatric, or other sensitive populations. Confirm any change with your healthcare provider before use.

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