Alfalfa leaf (Medicago sativa)
What it is
A leguminous forage crop that delivers chlorophyll, vitamin K, saponins, and phytoestrogens (coumestrol). Alfalfa saponins modestly lower cholesterol by binding intestinal cholesterol and bile acids — historical human studies showed 10-15% LDL reductions at high doses. Contraindicated in autoimmune conditions (particularly SLE) due to L-canavanine, which has triggered lupus flares and been implicated in drug-induced-lupus-like reactions. Sprouted seeds pose similar concerns.
Dose
500–1500 mg dried leaf or 5–10 mL liquid extract daily
Time of day & tips
Leaf is safer than seeds/sprouts (canavanine content); avoid in lupus, MS, and other autoimmune conditions; may interact with warfarin due to vitamin K
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