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68
SCORE

Aged garlic extract (Kyolic)

Cardiovascular · Blood pressure · Immune
Tier 2 — Promising

What it is

Regular garlic causes digestive upset and odour, but the aged extract form (Kyolic) is odourless and better tolerated. A meta-analysis by Ried (Exp Ther Med 2020) pooling 12 trials found aged garlic extract reduced systolic blood pressure by roughly 8 mmHg in hypertensive adults, with smaller effects in normotensive subjects. Coronary calcium trials (Budoff 2016) also suggest modestly reduced arterial plaque progression. The aging process converts harsh sulfur compounds into the gentler, more bioactive S-allyl cysteine.

Efficacy
3/5
Safety
5/5
Research
3/5
Onset
2/5
Cost
3/5
Drug-int.
4/5

Dose

600–1,200 mg/day aged garlic extract (standardised to S-allyl cysteine)

Time of day & tips

Take with food. Odourless so timing is flexible. Can be combined with omega-3s for cardiovascular support. Avoid with blood thinners at high doses.

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