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Supplements for eye health

Lutein, zeaxanthin, omega-3, and what AREDS2 actually showed.

AREDS2 confirmed lutein 10 mg + zeaxanthin 2 mg + zinc 25 mg + vitamin C 500 mg + vitamin E 400 IU reduces progression of intermediate-to-advanced AMD by ~25%. Adding omega-3 enhances macular pigment optical density (LUTEGA trial). Bilberry has small recent vision trials but evidence is preliminary. Avoid: standalone beta-carotene at AREDS doses if you smoke (lung cancer signal in CARET, ATBC). Astaxanthin has small eye-fatigue trials but the AMD data is thin.
77
Vitamin D3 liquid drops
Bone · Immunity · Flexible dosing
Tier 2
75
DHA (standalone, algal)
Brain · Pregnancy · Vegan
Tier 2
75
Algal DHA (vegan omega-3)
Brain health · Pregnancy · Vegan omega-3
Tier 2
73
Vitamin A (retinol, low-dose)
Vision · Immunity · Skin
Tier 2
69
Lutein + Zeaxanthin
Eye health · AMD
Tier 2
68
Zeaxanthin (standalone)
Eye health · Macular pigment · AMD
Tier 2
68
Lutein (standalone)
Eye health · Blue light · Macular
Tier 2
67
Bilberry extract
Eye health · Circulation · Antioxidant
Tier 2
66
Omega-3 DHA-dominant
Brain health · Pregnancy · Cognition
Tier 2
64
Idebenone
Mitochondrial · Cognition · Vision
Tier 2
62
Vitamin K2 (MK-7)
Bone · Vascular calcification
Tier 2
62
Hawthorn berry (Crataegus)
Heart failure · Blood pressure
Tier 2
60
St. John's Wort
Mild-moderate depression
Tier 2
60
White willow bark (Salix alba)
Pain · Inflammation · Back pain
Tier 2
60
Lycium barbarum (goji berry extract, standardised)
Eye health · Antioxidant · TCM longevity
Tier 2
59
Berberis aristata (Indian barberry)
Ayurveda · Glucose · Eye health
Tier 3
58
Vitamin E (mixed tocopherols)
Antioxidant · Skin · NAFLD
Tier 3
58
Blackcurrant extract
Eye health · Immunity · Circulation · Antioxidant
Tier 3
58
Potassium gluconate
Potassium form · Electrolyte
Tier 3
58
Calamari oil (high-DHA)
Omega-3 · DHA-rich · Sustainable
Tier 3
56
Mixed carotenoids
Antioxidant · Eye health · Skin
Tier 3
56
Ginkgo biloba EGb 761
Dementia symptoms · Circulation · Cognitive aging
Tier 3
56
Maqui berry (Aristotelia chilensis)
Antioxidant · Metabolic · Eye health
Tier 3
55
Eyebright (Euphrasia officinalis)
Eye health · Allergies · Conjunctivitis
Tier 3
54
Sea buckthorn oil (full spectrum)
Skin · Mucous membranes · Vaginal dryness
Tier 3
Educational reference, not medical advice. Discuss any supplement change with a qualified clinician before acting on this list.
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