Supplements for hormones
Thyroid, estrogen, testosterone — what's evidence-backed by life stage.
Hormonal claims are where supplement marketing diverges most from clinical evidence. Real, evidence-supported interventions include: selenium + iodine for thyroid (selenium-dependent deiodinases convert T4→T3), myo-inositol for PCOS, B6 + magnesium + calcium for PMS, soy isoflavones for hot flashes (East Asian women specifically). Most testosterone-boosting supplements (tribulus, fadogia, tongkat, fenugreek) have weak or null human evidence. DIM and I3C shift estrogen metabolism but with unclear clinical effect.
Evidence summary
The numbers on the cards are the same composite as the supplement pages: efficacy, safety, research, onset, cost, and drug-interaction ratings, from 20 to 100. The strongest records on this page are Zinc, Calcium, and Inositol myo-form (PCOS/metabolic). A higher score is a stronger record in the database, not a personal recommendation.
Who should be careful
- Pregnancy, breastfeeding, children, and anyone taking a prescription drug should talk with a clinician before using this list.
- Do not stack products from this list that sedate, thin the blood, or lower blood sugar with medicines that do the same thing.
Comparisons and topic guides
81
Zinc
64
Calcium
72
Inositol myo-form (PCOS/metabolic)
72
Lactobacillus casei Shirota
72
Bifidobacterium longum BB536
72
Lactobacillus helveticus/B. longum R0052/R0175
72
D-Chiro Inositol
70
Iron
70
Bifidobacterium longum
70
Lactobacillus reuteri
69
Saffron Affron (standardised extract)
68
Ashwagandha (KSM-66)
68
Evening primrose oil (EPO)
68
Pumpkin seed oil
67
Iodine
66
Fenugreek seed extract (Testofen / standardised)
65
PharmaGABA
64
Fenugreek (Trigonella foenum-graecum)
64
Vitex / Chasteberry (Vitex agnus-castus)
64
Phosphatidylserine
63
Inulin / FOS (prebiotic fibre)
63
Manganese
63
Magnolia bark (honokiol + magnolol)
62
Selenium
62
Vitamin B6 (P5P)
Educational reference, not medical advice. Discuss any supplement change with a qualified clinician before acting on this list.