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Supplements for heart

Cholesterol, blood pressure, and cardiovascular outcomes — by what the trials show.

Psyllium husk (FDA-recognised health claim, 7 g/day), oat beta-glucan (3 g/day), bergamot, red yeast rice (acts like a low-dose statin), and aged garlic extract have the strongest LDL-lowering evidence. Omega-3 at high dose lowers triglycerides but raises atrial-fibrillation risk by ~50% (O'Keefe 2024) — discuss with cardiology. Magnesium, hibiscus, hawthorn, and beetroot have BP-lowering data. CoQ10 ubiquinol is reasonable when on statins (statins deplete it).

Evidence summary

The numbers on the cards are the same composite as the supplement pages: efficacy, safety, research, onset, cost, and drug-interaction ratings, from 20 to 100. The strongest records on this page are Oat beta-glucan (cholesterol), Fibre (general dietary), and Psyllium husk (Plantago ovata). A higher score is a stronger record in the database, not a personal recommendation.

Who should be careful

Pregnancy, breastfeeding, children, and anyone taking a prescription drug should talk with a clinician before using this list.
Do not stack products from this list that sedate, thin the blood, or lower blood sugar with medicines that do the same thing.

Comparisons and topic guides

Oat beta-glucan (cholesterol)

LDL cholesterol · FDA health claim · Soluble fibre · Heart health · Evidence

Fibre (general dietary)

Gut · Heart · Glucose

Psyllium husk (Plantago ovata)

Cholesterol · Gut · Glucose

Vitamin B1 (Thiamine)

Nerve function · Energy metabolism · Deficiency

Sleep · Cognition · Metabolic

Potassium supplementation (clinical)

Blood pressure · Cardiovascular · Electrolyte

Bone · Muscle · Nerve

Male fertility · Cardiac · Fat metabolism · Exercise recovery

Omega-3 (EPA/DHA)

Cardiovascular · Inflammation

Calcium carbonate/citrate (bone health)

Bone density · Osteoporosis · Pregnancy

Phytosterols (beta-sitosterol complex)

Cholesterol · Heart

Nicotinic acid (Niacin, flush form)

Lipids · Cardiovascular · Vitamin B3

Lactobacillus acidophilus

Gut · Vaginal health · Cholesterol

DGL Licorice (deglycyrrhizinated)

GERD · Ulcer · Gut lining

Theaflavins (black tea extract)

Cardiovascular · Cholesterol · Antioxidant

Citrulline (L-citrulline, pure form)

Blood flow · Exercise · Blood pressure

Niacinamide (nicotinamide)

Knee OA · NAD precursor · Skin · No flush · B3 form

Acacia fiber (prebiotic)

Prebiotic · IBS · Cholesterol · Bifidobacterium · Gentle · SIBO-safe

Potassium citrate

Blood pressure · Muscle · Electrolyte

Beta-glucan (1,3/1,6)

Immunity · Cholesterol · Gut

Cacao flavanols

Cardiovascular · Cognition · Blood pressure

Omega-3 (high dose)

Drug interactions · Anticoagulants · Cardiovascular

CoQ10 (ubiquinone, classic form)

Mitochondrial · Antioxidant · Statin users · Converts to ubiquinol

Prostate · Cardiovascular · Skin

Educational reference, not medical advice. Discuss any supplement change with a qualified clinician before acting on this list.

See also: All symptoms · Compare two supplements · About