Butyrate tributyrin (odourless)

Tier 2 — promising · Gut integrity · Colon health · Microbiome

Tributyrin delivers butyrate to the colon where it fuels colonocytes and maintains gut barrier integrity. More stable and odourless than sodium butyrate, with less small-intestine degradation. Small human trials (Banasiewicz 2013 and others) suggest butyrate/tributyrin improves gut permeability markers and symptoms in IBD and IBS, though most evidence remains preliminary. Well tolerated.

Dose: 300–600 mg/day tributyrin; better colon delivery and palatability than sodium butyrate powder