Berberine
What it is
Lowers blood sugar, LDL cholesterol, triglycerides, and waist size — comparable to metformin in some head-to-head trials. A 2025 review confirms significant improvements across all metabolic markers. Warning: severe interactions with statins, metformin, diabetes drugs, and blood pressure meds (hypoglycemia, statin toxicity risk). Always consult your doctor before use.
Dose
500 mg × 2–3 daily with meals + piperine; medical supervision required if on any prescription medication
Time of day & tips
Always take with meals to slow absorption and reduce hypoglycaemia risk. Do not take on an empty stomach. Consult your doctor before starting if on any medication.
Cycling
Safe for continuous use under medical supervision. Monitor liver enzymes every 3-6 months. Some practitioners recommend 8 weeks on, 2 weeks off.
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